In my practice, clients frequently inquire about the supplements I suggest. When it comes to recommending supplements, I take into account each patient's medical history and specific symptoms. Among the various supplements, two are of particular interest - Collagen and Serum-Derived Bovine Immunoglobulins. Despite their distinct properties, these supplements are commonly mistaken for each other due to their origin from beef. Let's delve into the difference between the two:
Collagen
Collagen is the most abundant protein in the body. It is a fibrous protein that gives strength to connective tissues like bone, cartilage, skin, muscle, and tendons. Collagen helps makes connective tissue strong and resilient and allows them to withstand stretching.
Collage supplements are highly prevalent in the current supplement market. Human studies are lacking; however, some randomized controlled trials have found that collagen supplements can improve skin elasticity. Some other studies have indicated that this type of supplement can improve joint mobility and decrease joint pain.
Serum-Derived Bovine Immunoglobulins (SBI)
To begin, we must first understand what an immunoglobulin is. Immunoglobulins, also known as antibodies, are glycoprotein molecules produced by the white blood cells. They are critical to the functioning of the immune system as they recognize and bind to specific antigens including bacteria and viruses.
SBI are immunoglobulins derived from cattle. SBI is comprised of >50% IgG, 1% IgA, and 5% IgM. It is generally accepted that oral immunoglobulins promote gastrointestinal health and homeostasis. Upon oral consumption of SBI, the immunoglobulin promotes gastrointestinal health by improving the composition of GI microflora and increasing gut barrier function. When taken in concentrated amounts, the immunoglobulins can bind to inflammatory antigens, thereby increasing their size so they cannot cross the epithelial layer. This increase in size and inability for the antigens to cross the epithelial layer prevents an immune response. Moreover, SBI may help manage gut inflammation by allowing for normal regeneration and repair of the lining of the gastrointestinal tract.
What does this mean for you?
I believe that both Collagen and SBI can be beneficial for many (but not all!) patients. Make sure you are working with a physician or Registered Dietitian to ensure that this type of supplement is okay for you.
Below are some of my favorite brands!
MegaIgG 2000 by Microbiome Labs